Histotripsy: Scientists Use Sound Waves to Destroy Tumors Without Surgery

Researchers at the University of Michigan have been advancing histotripsy, a groundbreaking non-invasive technique that uses focused ultrasound waves to mechanically destroy tumors. Unlike thermal ablation, histotripsy works by creating tiny bubbles that rapidly expand and collapse, liquefying targeted tissue with extraordinary precision.

Dr. Zhen Xu, the inventor of the technology, explained that histotripsy can target tumors deep inside the body without making a single incision. The destroyed tumor fragments are then naturally absorbed by the body, and early evidence suggests the process may even stimulate an anti-tumor immune response.

“Unlike thermal ablation, histotripsy works by creating tiny bubbles that rapidly expand and collapse, liquefying targeted tissue with extraordinary precision.”

The FDA cleared histotripsy for liver tumors, and clinical trials are expanding to other cancer types. "This could change the way we treat cancer," said Dr. Xu. "Patients could potentially walk in, have their tumor destroyed, and go home the same day."