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The Breakthrough Prize Foundation awarded six $3 million prizes on April 18, 2026, recognizing pioneers who restored sight through gene therapy, cured sickle cell disease and mapped the genetic roots of ALS.
Researchers at the Mayo Clinic and AI interpretability startup Goodfire used the Evo 2 genomic foundation model to predict which DNA mutations cause disease — and to explain why — in work reported by TIME on April 14, 2026.
Researchers at Karolinska Institutet treated ten patients with a single injection delivering a working OTOF gene to the inner ear, with all showing clear hearing improvement within six months.
A new AI system published in Nature can diagnose rare diseases by integrating clinical data, genetic information, and medical literature searches. The system provides its underlying reasoning, helping doctors understand its conclusions. For patients who often wait years for a diagnosis, the technology could dramatically shorten the diagnostic odyssey.
Researchers at UC San Diego have developed a novel CRISPR-based genetic cassette that can spread between bacteria to actively dismantle antibiotic resistance genes — offering a powerful new weapon against the growing superbug crisis.
The gene-editing therapy Casgevy is now accessible in 30 nations including Nigeria and India, where sickle-cell disease is most prevalent.
UK doctors have reported a breakthrough in treating Huntington's disease, with a new gene therapy able to slow its progression by 75 percent. The treatment targets the faulty gene responsible for the devastating neurodegenerative condition that affects around 30,000 people in the UK alone.
UK doctors report a breakthrough in treating Huntington's disease, with a new gene therapy able to slow its progression by 75 percent.
Revolutionary gene therapy treatment has successfully helped people born with genetic hearing loss to recover some of their hearing, marking a new era in treating hereditary deafness.
A baby girl with a rare and fatal genetic disorder became the first person to receive a personalized CRISPR-based gene therapy, and is now thriving months after treatment.
A new conservation study offers hope for wild axolotls facing extinction: captive-bred populations retain enough genetic diversity to potentially replenish their wild counterparts in Mexico.
Researchers at the Arc Institute developed bridge recombinases, a revolutionary gene-editing tool that can insert or replace nearly 1 million DNA bases — far surpassing CRISPR's capabilities.
In a historic medical breakthrough, gene therapy has been used to significantly slow Huntington's disease for the first time.
A 71-year-old man with liver disease survived 171 days with a genetically modified pig liver, proving that animal organs can perform essential functions in humans.
The FDA-approved CRISPR therapy Casgevy has successfully cured sickle cell disease patients, with many now living pain-free after a single treatment.
